This is a two-parter, so consider yourself doubly warned. I've always admire the ambition of this series; trying to team Spidey up with everyone in the Marvel Universe no matter how little logic is involved. If Batman can team up with Kamandi, why can't Spidey meet Deathlok? Or Killraven? Or every monster in creation? This story follows a convoluted path and Spider-Man and Frankenstein get together (I honestly can't remember how) are both targeted to become some sort of Dr. Moreauvian plot to take over the world via an army of monsters. This silly plot, stretched over two issues by the inefficient Gerry Conway, fizzles out before it gets started.
Essentially, the all powerful mad scientist villain, whom had no problem capturing Spider-Man and the Frankenstein monster (twice), is ultimately defeated because he is (literally) caught napping. Seriously? Then he whimpers like the bad guy in a Scooby Doo cartoon. I know this is a funnybook, but I like my villains to go out with some degree of pride. There's also a lame Beauty and the Beast angle within the Man-Wolf subplot. S.H.I.E.L.D. seems displeased to have to clean this mess up at the end. Sal Buscema's pencils are rendered lifeless by Vinnie Colletta's inks. I know that he's an easy target, but this is a prime example of him hurting a story. This one is downright beastly, and not in the intended way.